Detalhe da pesquisa
1.
Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS.
N Engl J Med
; 387(12): 1099-1110, 2022 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36129998
2.
Identification of gene fusions associated with amyotrophic lateral sclerosis.
Muscle Nerve
; 69(4): 477-489, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38305586
3.
Debamestrocel multimodal effects on biomarker pathways in amyotrophic lateral sclerosis are linked to clinical outcomes.
Muscle Nerve
; 69(6): 719-729, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593477
4.
SOD1 Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS.
N Engl J Med
; 383(2): 151-158, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32640133
5.
Adaptive Platform Trials to Transform Amyotrophic Lateral Sclerosis Therapy Development.
Ann Neurol
; 91(2): 165-175, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34935174
6.
Expanded access protocol (EAP) program for access to investigational products for amyotrophic lateral sclerosis (ALS).
Muscle Nerve
; 67(6): 456-463, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36929648
7.
Randomized trial of inosine for urate elevation in amyotrophic lateral sclerosis.
Muscle Nerve
; 67(5): 378-386, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36840949
8.
A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis.
Muscle Nerve
; 65(3): 291-302, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34890069
9.
An expanded access protocol of RT001 in amyotrophic lateral sclerosis-Initial experience with a lipid peroxidation inhibitor.
Muscle Nerve
; 66(4): 421-425, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35765222
10.
Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis.
N Engl J Med
; 379(9): 846-855, 2018 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30157388
11.
Tocilizumab is safe and tolerable and reduces C-reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patients.
Muscle Nerve
; 64(3): 309-320, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34075589
12.
Effects of mexiletine on hyperexcitability in sporadic amyotrophic lateral sclerosis: Preliminary findings from a small phase II randomized controlled trial.
Muscle Nerve
; 63(3): 371-383, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33340120
13.
Amyotrophic lateral sclerosis care and research in the United States during the COVID-19 pandemic: Challenges and opportunities.
Muscle Nerve
; 62(2): 182-186, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32445195
14.
Sodium Phenylbutyrate-Taurursodiol for ALS. Reply.
N Engl J Med
; 383(23): 2294, 2020 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33264555
15.
Regulatory Approval in ALS; When Is a Single Study Enough?
Ann Neurol
; 91(6): 737-739, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35478359
16.
Natural history of infantile-onset spinal muscular atrophy.
Ann Neurol
; 82(6): 883-891, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29149772
17.
Mexiletine for muscle cramps in amyotrophic lateral sclerosis: A randomized, double-blind crossover trial.
Muscle Nerve
; 2018 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29510461
18.
Defining SOD1 ALS natural history to guide therapeutic clinical trial design.
J Neurol Neurosurg Psychiatry
; 88(2): 99-105, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27261500
19.
Fixed dynamometry is more sensitive than vital capacity or ALS rating scale.
Muscle Nerve
; 56(4): 710-715, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28120413
20.
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.
Ann Neurol
; 77(1): 75-99, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25381879